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Point mutation in the polyomavirus enhancer alters local DNA conformation.

A point mutation in the enhancer of polyomavirus host range mutant, PyEC F441, permits productive infection of the murine embryonal carcinoma cell line, F9. This mutation at nucleotide position 5258 introduces a local conformational change in naked viral DNA. The effect of all four possible nucleoti...

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Bibliografiske detaljer
Hovedforfatter: Fujimura, F K
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC338194/
https://ncbi.nlm.nih.gov/pubmed/2833724
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