Yüklüyor......
Inhibition of JAK2 Signaling by TG101209 Enhances Radiotherapy in Lung Cancer Models
INTRODUCTION: Persistent STAT3 activation contributes to lung carcinogenesis. Survivin, one of STAT3-regulated genes, is antiapoptotic and confers cancer radioresistance. METHODS: We tested whether TG101209, a small-molecule inhibitor of JAK2 (a STAT3-activating tyrosine kinase), affected survivin e...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3104103/ https://ncbi.nlm.nih.gov/pubmed/21325979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e31820d9d11 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|