THE ROLE OF IGF-1 SIGNALING PATHWAY IN CISPLATIN-RESISTANT LUNG CANCER CELLS

PURPOSE: The development of drug-resistant phenotypes has been a major obstacle to Cisplatin (CDDP) use in non-small cell lung cancer (NSCLC). We aimed to identify some of the molecular mechanisms that underlie CDDP resistance by using microarray expression analysis. METHODS AND MATERIALS: H460 cell...

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Autors principals: Sun, Yunguang, Zheng, Siyuan, Torossian, Artour, Speirs, Christina K., Schleicher, Stephen, Giacalone, Nicholas J., Carbone, David P., Zhao, Zhongming, Lu, Bo
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271860/
https://ncbi.nlm.nih.gov/pubmed/22197230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2011.06.1999
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