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Assessment of M867, a selective caspase-3 inhibitor, in an orthotopic mouse model for non-small cell lung carcinoma

Radiation-induced lung injury (RILI) is a significant dose limiting complication of thoracic radiation for lung, breast, and esophageal cancer. Strategies for increasing the therapeutic index of radiation involve the use of radiosensitizing agents. We investigated the potential of M867 to sensitize...

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Hlavní autoři: Li, Bo, Blanc, Justin M Le, Sun, Yunguang, Yang, Lifeng, Zaorsky, Nicholas G, Giacalone, Nicholas J, Torossian, Artour, Lu, Bo
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960453/
https://ncbi.nlm.nih.gov/pubmed/24660105
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