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Identification of anti-inflammatory targets for Huntington’s disease using a brain slice-based screening assay

Huntington’s disease (HD) is a late-onset, neurodegenerative disease for which there are currently no cures nor disease-modifying treatments. Here we report the identification of several potential anti-inflammatory targets for HD using an ex vivo model of HD that involves the acute transfection of h...

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Detalhes bibliográficos
Main Authors: Reinhart, Peter H., Kaltenbach, Linda S., Essrich, Christian, Dunn, Denise E., Eudailey, Joshua A., DeMarco, C. Todd, Turmel, Gregory J., Whaley, Jennifer C., Wood, Andrew, Cho, Seongeon, Lo, Donald C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104027/
https://ncbi.nlm.nih.gov/pubmed/21458569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.03.017
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