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Crystal Structure of a Phenol-coupling P450 Monooxygenase Involved in Teicoplanin Biosynthesis

The lipoglycopeptide antibiotic teicoplanin has proven efficacy against gram-positive pathogens. Teicoplanin is distinguished from the vancomycin-type glycopeptide antibiotics, by the presence of an additional cross-link between the aromatic amino acids 1 and 3 that is catalyzed by the cytochrome P4...

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Detalhes bibliográficos
Main Authors: Li, Zhi, Rupasinghe, Sanjeewa G., Schuler, Mary A., Nair, Satish K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103887/
https://ncbi.nlm.nih.gov/pubmed/21445994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22996
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