Involvement of a Cytochrome P450 Monooxygenase in Thaxtomin A Biosynthesis by Streptomyces acidiscabies

The biosynthesis of the thaxtomin cyclic dipeptide phytotoxins proceeds nonribosomally via the thiotemplate mechanism. Acyladenylation, thioesterification, N-methylation, and cyclization of two amino acid substrates are catalyzed by the txtAB-encoded thaxtomin synthetase. Nucleotide sequence analysi...

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Autori principali: Healy, F. G., Krasnoff, S. B., Wach, M., Gibson, D. M., Loria, R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
Soggetti:
Plant Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC134914/
https://ncbi.nlm.nih.gov/pubmed/11889110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.7.2019-2029.2002
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