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Af17 Deficiency Increases Sodium Excretion and Decreases Blood Pressure
The putative transcription factor AF17 upregulates the transcription of the epithelial sodium channel (ENaC) genes, but whether AF17 modulates sodium homeostasis and BP is unknown. Here, we generated Af17-deficient mice to determine whether deletion of Af17 leads to sodium wasting and low BP. Compar...
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| Hauptverfasser: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Nephrology
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103727/ https://ncbi.nlm.nih.gov/pubmed/21546577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010121270 |
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