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Af17 Deficiency Increases Sodium Excretion and Decreases Blood Pressure

The putative transcription factor AF17 upregulates the transcription of the epithelial sodium channel (ENaC) genes, but whether AF17 modulates sodium homeostasis and BP is unknown. Here, we generated Af17-deficient mice to determine whether deletion of Af17 leads to sodium wasting and low BP. Compar...

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Main Authors: Chen, Lihe, Wu, Hongyu, Pochynyuk, Oleh M., Reisenauer, Mary Rose, Zhang, Zhijing, Huang, Le, Zaika, Oleg Leonidovych, Mamenko, Mykola, Zhang, Weiru, Zhou, Qiaoling, Liu, Mingyao, Xia, Yang, Zhang, Wenzheng
格式: Artigo
語言:Inglês
出版: American Society of Nephrology 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103727/
https://ncbi.nlm.nih.gov/pubmed/21546577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010121270
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