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Origins of the High Catalytic Activity of Human Alcohol Dehydrogenase 4 Studied with Horse Liver A317C Alcohol Dehydrogenase
The turnover numbers and other kinetic constants for human alcohol dehydrogenase (ADH) 4 (“stomach” isoenzyme) are substantially larger (10–100-fold) than those for human class I and horse liver alcohol dehydrogenases. Comparison of the primary amino acid sequences (69% identity) and tertiary struct...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103598/ https://ncbi.nlm.nih.gov/pubmed/21184752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2010.12.015 |
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