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Contribution of buried distal amino acid residues in horse liver alcohol dehydrogenase to structure and catalysis
The dynamics of enzyme catalysis range from the slow time scale (∼ms) for substrate binding and conformational changes to the fast time (∼ps) scale for reorganization of substrates in the chemical step. The contribution of global dynamics to catalysis by alcohol dehydrogenase was tested by substitut...
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| 出版年: | Protein Sci |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5818739/ https://ncbi.nlm.nih.gov/pubmed/29271062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3370 |
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