Heterotrimeric G(i) Proteins Link Hedgehog Signaling to Activation of Rho Small GTPases to Promote Fibroblast Migration

Evidence supporting the functionality of Smoothened (SMO), an essential transducer in most pathways engaged by Hedgehog (Hh), as a G(i)-coupled receptor contrasts with the lack of an apparently consistent requirement for G(i) in Hh signal transduction. In the present study, we sought to evaluate the...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Polizio, Ariel H., Chinchilla, Pilar, Chen, Xiaole, Kim, Sangbumn, Manning, David R., Riobo, Natalia A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2011
Ämnen:
Signal Transduction
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103338/
https://ncbi.nlm.nih.gov/pubmed/21474452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.197111
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk