Heterotrimeric G(i) Proteins Link Hedgehog Signaling to Activation of Rho Small GTPases to Promote Fibroblast Migration

Evidence supporting the functionality of Smoothened (SMO), an essential transducer in most pathways engaged by Hedgehog (Hh), as a G(i)-coupled receptor contrasts with the lack of an apparently consistent requirement for G(i) in Hh signal transduction. In the present study, we sought to evaluate the...

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Detaylı Bibliyografya
Asıl Yazarlar: Polizio, Ariel H., Chinchilla, Pilar, Chen, Xiaole, Kim, Sangbumn, Manning, David R., Riobo, Natalia A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2011
Konular:
Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103338/
https://ncbi.nlm.nih.gov/pubmed/21474452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.197111
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