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Heterotrimeric G(i) Proteins Link Hedgehog Signaling to Activation of Rho Small GTPases to Promote Fibroblast Migration

Evidence supporting the functionality of Smoothened (SMO), an essential transducer in most pathways engaged by Hedgehog (Hh), as a G(i)-coupled receptor contrasts with the lack of an apparently consistent requirement for G(i) in Hh signal transduction. In the present study, we sought to evaluate the...

詳細記述

保存先:
書誌詳細
主要な著者: Polizio, Ariel H., Chinchilla, Pilar, Chen, Xiaole, Kim, Sangbumn, Manning, David R., Riobo, Natalia A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103338/
https://ncbi.nlm.nih.gov/pubmed/21474452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.197111
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