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High Avidity Binding to DNA Protects Ubiquitylated Substrates from Proteasomal Degradation
Protein domains that act as degradation and stabilization signals regulate the rate of turnover of proteasomal substrates. Here we report that the bipartite Gly-Arg repeat of the Epstein-Barr virus (EBV) nuclear antigen (EBNA)-1 acts as a stabilization signal that inhibits proteasomal degradation in...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103336/ https://ncbi.nlm.nih.gov/pubmed/21471195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.224782 |
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