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High Avidity Binding to DNA Protects Ubiquitylated Substrates from Proteasomal Degradation
Protein domains that act as degradation and stabilization signals regulate the rate of turnover of proteasomal substrates. Here we report that the bipartite Gly-Arg repeat of the Epstein-Barr virus (EBV) nuclear antigen (EBNA)-1 acts as a stabilization signal that inhibits proteasomal degradation in...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103336/ https://ncbi.nlm.nih.gov/pubmed/21471195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.224782 |
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