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Activity-Dependent IGF-1 Exocytosis is Controlled by the Ca(2+)-Sensor Synaptotagmin-10
Synaptotagmins Syt1, Syt2, Syt7, and Syt9 act as Ca(2+)-sensors for synaptic and neuroendocrine exocytosis, but the function of other synaptotagmins remains unknown. Here, we show that olfactory bulb neurons secrete IGF-1 by an activity-dependent pathway of exocytosis, and that Syt10 functions as th...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3102833/ https://ncbi.nlm.nih.gov/pubmed/21496647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.03.034 |
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