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Age-associated inflammation and Toll-like receptor dysfunction prime the lungs for pneumococcal pneumonia
BACKGROUND: Aging is associated with increased inflammation and risk for community-acquired pneumonia (CAP). Streptococcus pneumoniae co-opts the NFkB-regulated proteins Polymeric immunoglobulin receptor (pIgR) and Platelet-activating factor receptor (PAFr) to attach and invade cells. We sought to d...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3102250/ https://ncbi.nlm.nih.gov/pubmed/19586419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/600870 |
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