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Elevated A20 contributes to age-dependent macrophage dysfunction in the lungs

Advanced age is associated with chronic low-grade inflammation (i.e. inflamm-aging) and poor macrophage function that includes a weak pro-inflammatory cytokine response to bacteria and diminished phagocytosis (i.e. age-dependent macrophage dysfunction [ADMD]). One reason for this is that ADMD is ass...

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Detalhes bibliográficos
Main Authors: Hinojosa, Cecilia A., Babu, Ramya Akula Suresh, Rahman, M., Fernandes, Gabriel, Boyd, Angela R., Orihuela, Carlos J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989429/
https://ncbi.nlm.nih.gov/pubmed/24440463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2014.01.007
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