Mitochondrial dysfunction contributes to the senescent phenotype of IPF lung fibroblasts

Increasing evidence highlights that senescence plays an important role in idiopathic pulmonary fibrosis (IPF). This study delineates the specific contribution of mitochondria and the superoxide they form to the senescent phenotype of lung fibroblasts from IPF patients (IPF‐LFs). Primary cultures of...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Schuliga, Michael, Pechkovsky, Dmitri V, Read, Jane, Waters, David W, Blokland, Kaj E C, Reid, Andrew T, Hogaboam, Cory M, Khalil, Nasreen, Burgess, Janette K, Prêle, Cecilia M, Mutsaers, Steven E, Jaffar, Jade, Westall, Glen, Grainge, Christopher, Knight, Darryl A
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237609/
https://ncbi.nlm.nih.gov/pubmed/30255990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13855
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