Senescence of IPF Lung Fibroblasts Disrupt Alveolar Epithelial Cell Proliferation and Promote Migration in Wound Healing

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease marked by excessive accumulation of lung fibroblasts (LFs) and collagen in the lung parenchyma. The mechanisms that underlie IPF pathophysiology are thought to reflect repeated alveolar epithelial injury leading to an aberrant wound r...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Blokland, Kaj E. C., Waters, David W., Schuliga, Michael, Read, Jane, Pouwels, Simon D., Grainge, Christopher L., Jaffar, Jade, Westall, Glen, Mutsaers, Steven E., Prêle, Cecilia M., Burgess, Janette K., Knight, Darryl A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238173/
https://ncbi.nlm.nih.gov/pubmed/32344567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12040389
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