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Crystal structures of the free and inhibited forms of plasmepsin I (PMI) from Plasmodium falciparum

Plasmepsin I (PMI) is one of the four vacuolar pepsin-like proteases responsible for hemoglobin degradation by the malarial parasite Plasmodium falciparum, and the only one with no crystal structure reported to date. Due to substantial functional redundancy of these enzymes, lack of inhibition of ev...

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Bibliografiset tiedot
Päätekijät: Bhaumik, Prasenjit, Horimoto, Yasumi, Xiao, Huogen, Miura, Takuya, Hidaka, Koushi, Kiso, Yoshiaki, Wlodawer, Alexander, Yada, Rickey Y., Gustchina, Alla
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102120/
https://ncbi.nlm.nih.gov/pubmed/21521654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2011.04.009
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