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Deciphering the mechanism of potent peptidomimetic inhibitors targeting Plasmepsins: Biochemical and structural insights
Malaria is a deadly disease killing worldwide hundreds of thousands people each year and the responsible parasite has acquired resistance to the available drug combinations. The four vacuolar plasmepsins (PMs) in Plasmodium falciparum involved in hemoglobin catabolism represent promising targets to...
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| Publicado no: | FEBS J |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6309945/ https://ncbi.nlm.nih.gov/pubmed/29943906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14598 |
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