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Five Additional Genes Are Involved in Clavulanic Acid Biosynthesis in Streptomyces clavuligerus

An approximately 12.5-kbp region of DNA sequence from beyond the end of the previously described clavulanic acid gene cluster was analyzed and found to encode nine possible open reading frames (ORFs). Involvement of these ORFs in clavulanic acid biosynthesis was assessed by creating mutants with def...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Jensen, S. E., Paradkar, A. S., Mosher, R. H., Anders, C., Beatty, P. H., Brumlik, M. J., Griffin, A., Barton, B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Chemistry; Biosynthesis
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310172/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14693539/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.1.192-202.2004
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