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The Paralogous Pairs of Genes Involved in Clavulanic Acid and Clavam Metabolite Biosynthesis Are Differently Regulated in Streptomyces clavuligerus

Carboxyethylarginine synthase, encoded by the paralogous ceaS1 and ceaS2 genes, catalyzes the first reaction in the shared biosynthetic pathway leading to clavulanic acid and the other clavam metabolites in Streptomyces clavuligerus. The nutritional regulation of ceaS1 and ceaS2 expression was analy...

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Detalhes bibliográficos
Main Authors: Tahlan, Kapil, Anders, Cecilia, Jensen, Susan E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC515150/
https://ncbi.nlm.nih.gov/pubmed/15342599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.18.6286-6297.2004
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