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The Paralogous Pairs of Genes Involved in Clavulanic Acid and Clavam Metabolite Biosynthesis Are Differently Regulated in Streptomyces clavuligerus

Carboxyethylarginine synthase, encoded by the paralogous ceaS1 and ceaS2 genes, catalyzes the first reaction in the shared biosynthetic pathway leading to clavulanic acid and the other clavam metabolites in Streptomyces clavuligerus. The nutritional regulation of ceaS1 and ceaS2 expression was analy...

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Autors principals: Tahlan, Kapil, Anders, Cecilia, Jensen, Susan E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC515150/
https://ncbi.nlm.nih.gov/pubmed/15342599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.18.6286-6297.2004
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