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The Paralogous Pairs of Genes Involved in Clavulanic Acid and Clavam Metabolite Biosynthesis Are Differently Regulated in Streptomyces clavuligerus
Carboxyethylarginine synthase, encoded by the paralogous ceaS1 and ceaS2 genes, catalyzes the first reaction in the shared biosynthetic pathway leading to clavulanic acid and the other clavam metabolites in Streptomyces clavuligerus. The nutritional regulation of ceaS1 and ceaS2 expression was analy...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2004
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC515150/ https://ncbi.nlm.nih.gov/pubmed/15342599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.18.6286-6297.2004 |
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