Five Additional Genes Are Involved in Clavulanic Acid Biosynthesis in Streptomyces clavuligerus

An approximately 12.5-kbp region of DNA sequence from beyond the end of the previously described clavulanic acid gene cluster was analyzed and found to encode nine possible open reading frames (ORFs). Involvement of these ORFs in clavulanic acid biosynthesis was assessed by creating mutants with def...

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Detalhes bibliográficos
Main Authors: Jensen, S. E., Paradkar, A. S., Mosher, R. H., Anders, C., Beatty, P. H., Brumlik, M. J., Griffin, A., Barton, B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Chemistry; Biosynthesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC310172/
https://ncbi.nlm.nih.gov/pubmed/14693539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.1.192-202.2004
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