Five Additional Genes Are Involved in Clavulanic Acid Biosynthesis in Streptomyces clavuligerus

An approximately 12.5-kbp region of DNA sequence from beyond the end of the previously described clavulanic acid gene cluster was analyzed and found to encode nine possible open reading frames (ORFs). Involvement of these ORFs in clavulanic acid biosynthesis was assessed by creating mutants with def...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Jensen, S. E., Paradkar, A. S., Mosher, R. H., Anders, C., Beatty, P. H., Brumlik, M. J., Griffin, A., Barton, B.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2004
Soggetti:	Chemistry; Biosynthesis
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310172/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14693539/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.1.192-202.2004
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