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Structure of even/odd trinucleotide repeat sequences modulates persistence of non-B conformations and conversion to duplex
Expansion of trinucleotide repeats (TNR) has been implicated in the emergence of neurodegenerative diseases. Formation of non-B conformations such as hairpins by these repeat sequences during DNA replication and/or repair has been proposed as a contributing factor to expansion. In this work we emplo...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3101280/ https://ncbi.nlm.nih.gov/pubmed/21526744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200397b |
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