Mitochondrial dysfunction in NnaD mutant flies and Purkinje cell degeneration (pcd) mice reveals a role for Nna proteins in neuronal bioenergetics

The Purkinje cell degeneration (pcd) mouse is a recessive model of neurodegeneration, involving cerebellum and retina. Purkinje cell death in pcd is dramatic, as >99% of Purkinje neurons are lost in three weeks. Loss-of-function of Nna1 causes pcd, and Nna1 is a highly conserved zinc carboxypepti...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Chakrabarti, Lisa, Zahra, Rabaab, Jackson, Stephen M., Kazemi-Esfarjani, Parsa, Sopher, Bryce L., Mason, Amanda G., Toneff, Thomas, Ryu, Soyoung, Shaffer, Scott, Kansy, Janice W., Eng, Jeremiah, Merrihew, Gennifer, MacCoss, Michael J., Murphy, Anne, Goodlett, David R., Hook, Vivian, Bennett, Craig L., Pallanck, Leo, La Spada, Albert R.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101252/
https://ncbi.nlm.nih.gov/pubmed/20620870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.05.024
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker