Behavioral and Cellular Modulation of l-DOPA-Induced Dyskinesia by β-Adrenoceptor Blockade in the 6-Hydroxydopamine-Lesioned Rat

Chronic dopamine replacement therapy in Parkinson's disease (PD) leads to deleterious motor sequelae known as l-DOPA-induced dyskinesia (LID). No known therapeutic can eliminate LID, but preliminary evidence suggests that dl-1-isopropylamino-3-(1-naphthyloxy)-2-propanol [(±)propranolol], a nons...

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Hlavní autoři: Lindenbach, David, Ostock, Corinne Y., Eskow Jaunarajs, Karen L., Dupre, Kristin B., Barnum, Christopher J., Bhide, Nirmal, Bishop, Christopher
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2011
Témata:
Behavioral Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101009/
https://ncbi.nlm.nih.gov/pubmed/21402691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.179416
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