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Effects of the beta-adrenergic receptor antagonist Propranolol on dyskinesia and L-DOPA-induced striatal DA efflux in the hemi-parkinsonian rat

Dopamine (DA) replacement therapy with L-DOPA continues to be the primary treatment of Parkinson's disease; however, long-term therapy is accompanied by L-DOPA-induced dyskinesias (LID). Several experimental and clinical studies have established that Propranolol, a β-adrenergic receptor antagon...

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Pubblicato in:J Neurochem
Autori principali: Bhide, Nirmal, Lindenbach, David, Barnum, Christopher J., George, Jessica A., Surrena, Margaret A., Bishop, Christopher
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490965/
https://ncbi.nlm.nih.gov/pubmed/25866285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13125
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