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Behavioral and neurochemical effects of chronic L-DOPA treatment on non-motor sequelae in the hemiparkinsonian rat

Depression and anxiety are prevalent non-motor symptoms that worsen quality of life for Parkinson’s disease (PD) patients. While dopamine (DA) cell loss is a commonly proposed mechanism, the reported efficacy of DA replacement therapy with L-DOPA on affective symptoms is inconsistent. In order to de...

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Detalhes bibliográficos
Main Authors: Eskow Jaunarajs, Karen L., Dupre, Kristin B., Ostock, Corinne Y., Button, Thomas, Deak, Terrence, Bishop, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953710/
https://ncbi.nlm.nih.gov/pubmed/20838211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0b013e32833e7e80
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