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Effects of 5-HT1A receptor stimulation on striatal and cortical M1 pERK induction by L-DOPA and a D1 receptor agonist in a rat model of Parkinson’s disease

Motor symptoms of Parkinson’s disease are commonly treated using L-DOPA although long-term treatment usually causes debilitating motor side effects including dyskinesias. A putative source of dyskinesia is abnormally high levels of phosphorylated extracellular-regulated kinase (pERK) within the stri...

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Detalhes bibliográficos
Main Authors: Lindenbach, David, Dupre, Kristin B., Eskow Jaunarajs, Karen L., Ostock, Corinne Y., Goldenberg, Adam A., Bishop, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825206/
https://ncbi.nlm.nih.gov/pubmed/24060645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2013.09.020
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