TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity

The trace amine-associated receptor 1 (TAAR1), activated by endogenous metabolites of amino acids like the trace amines p-tyramine and β-phenylethylamine, has proven to be an important modulator of the dopaminergic system and is considered a promising target for the treatment of neuropsychiatric dis...

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Главные авторы: Revel, Florent G., Moreau, Jean-Luc, Gainetdinov, Raul R., Bradaia, Amyaouch, Sotnikova, Tatyana D., Mory, Roland, Durkin, Sean, Zbinden, Katrin Groebke, Norcross, Roger, Meyer, Claas A., Metzler, Veit, Chaboz, Sylvie, Ozmen, Laurence, Trube, Gerhard, Pouzet, Bruno, Bettler, Bernhard, Caron, Marc G., Wettstein, Joseph G., Hoener, Marius C.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2011
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101002/
https://ncbi.nlm.nih.gov/pubmed/21525407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103029108
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