TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity

The trace amine-associated receptor 1 (TAAR1), activated by endogenous metabolites of amino acids like the trace amines p-tyramine and β-phenylethylamine, has proven to be an important modulator of the dopaminergic system and is considered a promising target for the treatment of neuropsychiatric dis...

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Detalhes bibliográficos
Main Authors: Revel, Florent G., Moreau, Jean-Luc, Gainetdinov, Raul R., Bradaia, Amyaouch, Sotnikova, Tatyana D., Mory, Roland, Durkin, Sean, Zbinden, Katrin Groebke, Norcross, Roger, Meyer, Claas A., Metzler, Veit, Chaboz, Sylvie, Ozmen, Laurence, Trube, Gerhard, Pouzet, Bruno, Bettler, Bernhard, Caron, Marc G., Wettstein, Joseph G., Hoener, Marius C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101002/
https://ncbi.nlm.nih.gov/pubmed/21525407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103029108
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