TAAR1 activation modulates monoaminergic neurotransmission, preventing hyperdopaminergic and hypoglutamatergic activity

The trace amine-associated receptor 1 (TAAR1), activated by endogenous metabolites of amino acids like the trace amines p-tyramine and β-phenylethylamine, has proven to be an important modulator of the dopaminergic system and is considered a promising target for the treatment of neuropsychiatric dis...

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Hlavní autoři: Revel, Florent G., Moreau, Jean-Luc, Gainetdinov, Raul R., Bradaia, Amyaouch, Sotnikova, Tatyana D., Mory, Roland, Durkin, Sean, Zbinden, Katrin Groebke, Norcross, Roger, Meyer, Claas A., Metzler, Veit, Chaboz, Sylvie, Ozmen, Laurence, Trube, Gerhard, Pouzet, Bruno, Bettler, Bernhard, Caron, Marc G., Wettstein, Joseph G., Hoener, Marius C.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101002/
https://ncbi.nlm.nih.gov/pubmed/21525407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103029108
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