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Beyond knockout rats: New insights into finer genome manipulation in rats

The ability to “knockout” specific genes in mice via embryonic stem (ES) cell-based gene-targeting technology has significantly enriched our understanding of gene function in normal and disease phenotypes. Improvements on this original strategy have been developed to enable the manipulation of genom...

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Autors principals: Huang, Guanyi, Tong, Chang, Kumbhani, Dhruv S, Ashton, Charles, Yan, Hexin, Ying, Qi-Long
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100883/
https://ncbi.nlm.nih.gov/pubmed/21383544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.7.15233
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