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Beyond knockout rats: New insights into finer genome manipulation in rats
The ability to “knockout” specific genes in mice via embryonic stem (ES) cell-based gene-targeting technology has significantly enriched our understanding of gene function in normal and disease phenotypes. Improvements on this original strategy have been developed to enable the manipulation of genom...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Landes Bioscience
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3100883/ https://ncbi.nlm.nih.gov/pubmed/21383544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.7.15233 |
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