Protein expression profiles of C3H 10T1/2 murine fibroblasts and of isogenic cells transformed by the H1047R mutant of phosphoinositide 3-kinase (PI3K)

We have used stable isotope labeling with amino acids in cell culture (SILAC) in conjunction with tandem mass spectrometry to characterize the proteomes of two isogenic cell lines that differ in the expression of a single oncoprotein, p110α of PI3K, carrying the H1047R mutation. 51,510 peptides were...

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Hlavní autoři: Hart, Jonathan Ross, Liao, Lujian, Ueno, Lynn, Yates, John R, Vogt, Peter K
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100876/
https://ncbi.nlm.nih.gov/pubmed/21350335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.6.15077
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