Wordt geladen...
Essential role of Stat3 in PI3K-induced oncogenic transformation
Cells transformed by the p110α-H1047R mutant of PI3K show increased tyrosine phosphorylation of Stat3. This activation of Stat3 is important for the transformation process, because a dominant-negative mutant of Stat3 interferes with PI3K-induced oncogenesis. GDC-0941, a specific inhibitor of PI3K re...
Bewaard in:
| Hoofdauteurs: | , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2011
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3156164/ https://ncbi.nlm.nih.gov/pubmed/21788516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110486108 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|