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MUC1-C oncoprotein suppresses reactive oxygen species–induced terminal differentiation of acute myelogenous leukemia cells

Acute myeloid leukemia (AML) cells are characterized by unlimited self-renewal and an impaired capacity to undergo terminal differentiation. The MUC1 oncoprotein is aberrantly expressed in AML cells; however, there has been no evidence for involvement of MUC1 in myeloid leukemogenesis. Cell-penetrat...

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Detalhes bibliográficos
Main Authors: Yin, Li, Wu, Zekui, Avigan, David, Rosenblatt, Jacalyn, Stone, Richard, Kharbanda, Surender, Kufe, Donald
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100696/
https://ncbi.nlm.nih.gov/pubmed/21422470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-10-296632
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