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MUC1-C Oncoprotein Blocks Terminal Differentiation of Chronic Myelogenous Leukemia Cells by a ROS-Mediated Mechanism

Chronic myelogenous leukemia (CML) inevitably progresses to a blast phase by mechanisms that are not well understood. The MUC1-C oncoprotein is expressed in CML blasts but not chronic phase cells. The present studies demonstrate that treatment of KU812 and K562 CML cells with a cell-penetrating MUC1...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Yin, Li, Kufe, Donald
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: SAGE Publications 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107545/
https://ncbi.nlm.nih.gov/pubmed/21643558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911405044
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