Survival of Human Multiple Myeloma Cells Is Dependent on MUC1 C-Terminal Transmembrane Subunit Oncoprotein Function

The MUC1 C-terminal transmembrane subunit (MUC1-C) oncoprotein is a direct activator of the canonical nuclear factor-κB (NF-κB) RelA/p65 pathway and is aberrantly expressed in human multiple myeloma cells. However, it is not known whether multiple myeloma cells are sensitive to the disruption of MUC...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yin, Li, Ahmad, Rehan, Kosugi, Michio, Kufe, Turner, Vasir, Baldev, Avigan, David, Kharbanda, Surender, Kufe, Donald
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Pharmacology and Experimental Therapeutics 2010
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917857/
https://ncbi.nlm.nih.gov/pubmed/20444960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.065011
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