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MUC1-C Oncoprotein Promotes STAT3 Activation in an Autoinductive Regulatory Loop
Signal transducer and activator of transcription 3 (STAT3) is activated in human breast cancer and other malignancies. Mucin 1 (MUC1) is a heterodimeric cell surface glycoprotein that is overexpressed in human carcinomas and, like STAT3, promotes cell survival and induces transformation. Here, we sh...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3070357/ https://ncbi.nlm.nih.gov/pubmed/21325207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2001426 |
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