Differential Effects of Antipsychotic Medications on Polyunsaturated Fatty Acid Biosynthesis in Rats: Relationship with Liver Delta6-Desaturase Expression

Polyunsaturated fatty acids (PUFA), a lipid family comprised of omega-3 (n-3) and n-6 fatty acids, are a critical component of cellular membranes, and recent in vitro studies have found that antipsychotic medications up-regulate genes responsible for PUFA biosynthesis. To evaluate this effect in viv...

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Main Authors: McNamara, Robert K., Jandacek, Ronald, Rider, Therese, Tso, Patrick, Cole-Strauss, Allyson, Lipton, Jack W.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100388/
https://ncbi.nlm.nih.gov/pubmed/21458237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2011.03.006
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