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The Aging Human Orbitofrontal Cortex: Decreasing Polyunsaturated Fatty Acid Composition and Associated Increases in Lipogenic Gene Expression and Stearoyl-CoA Desaturase Activity

Orbitofrontal cortex (OFC, Brodmann area 10) gray matter volume reductions and selective reductions in docosahexaenoic acid (DHA, 22:6n-3) are observed in adult patients with major depressive disorder (MDD). OFC gray matter volume also decreases with advancing age in healthy subjects. To examine if...

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Detalhes bibliográficos
Main Authors: McNamara, Robert K., Liu, Yanhong, Jandacek, Ronald, Rider, Therese, Tso, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494852/
https://ncbi.nlm.nih.gov/pubmed/18499418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plefa.2008.04.001
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