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Atypical Antipsychotic Medications Increase Postprandial Triglyceride and Glucose Levels in Male Rats: Relationship with Stearoyl-CoA Desaturase Activity

Recent preclinical and clinical evidence suggests that the stearoyl-CoA desaturase-1 (Scd1) enzyme plays a key role in the regulation of triglyceride (TG) biosynthesis and insulin sensitivity, and in vitro studies have found that antipsychotic medications up-regulate Scd1 mRNA expression. To investi...

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Bibliografiska uppgifter
Huvudupphovsmän: McNamara, Robert K., Jandacek, Ronald, Rider, Therese, Tso, Patrick, Cole-Strauss, Allyson, Lipton, Jack W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100393/
https://ncbi.nlm.nih.gov/pubmed/21474290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2011.03.016
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