Omega-3 Fatty Acid Deficiency Augments Risperidone-Induced Hepatic Steatosis in Rats: Positive Association with Stearoyl-CoA Desaturase

Psychiatric patients frequently exhibit long-chain n-3 (LCn-3) fatty acid deficits and elevated triglyceride (TAG) production following chronic exposure to second generation antipsychotics (SGA). Emerging evidence suggests that SGAs and LCn-3 fatty acids have opposing effects on stearoyl-CoA desatur...

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Главные авторы: McNamara, Robert K., Magrisso, I. Jack, Hofacer, Rylon, Jandacek, Ronald, Rider, Therese, Tso, Patrick, Benoit, Stephen C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419281/
https://ncbi.nlm.nih.gov/pubmed/22750665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2012.06.010
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