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Leaky sodium channels from voltage sensor mutations in periodic paralysis, but not paramyotonia
BACKGROUND: Hypokalemic periodic paralysis (HypoPP) is associated with mutations in either the Ca(V)1.1 calcium channel or the Na(V)1.4 sodium channel. Some Na(V)1.4 HypoPP mutations have been shown to cause an anomalous inward current that may contribute to the attacks of paralysis. Herein, we test...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Lippincott Williams & Wilkins
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3100087/ https://ncbi.nlm.nih.gov/pubmed/21490317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e318219fb57 |
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