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The Human Skeletal Muscle Na Channel Mutation R669H Associated with Hypokalemic Periodic Paralysis Enhances Slow Inactivation

Missense mutations of the human skeletal muscle voltage-gated Na channel (hSkM1) underlie a variety of diseases, including hyperkalemic periodic paralysis (HyperPP), paramyotonia congenita, and potassium-aggravated myotonia. Another disorder of sarcolemmal excitability, hypokalemic periodic paralysi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Struyk, Arie F., Scoggan, Kylie A., Bulman, Dennis E., Cannon, Stephen C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773093/
https://ncbi.nlm.nih.gov/pubmed/11102465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-23-08610.2000
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